Abstract #2429

A preliminary study of 3D-amide proton transfer MR imaging in rectal adenocarcinoma: comparison with diffusion kurtosis imaging

Weicui Chen¹, Ling Li², Yingjie Mei³, Jilei Zhang³, Weikang Huang¹, Bo Liu¹, and Xian Liu¹

¹Radiology, The second Affiliated hospital of Guangzhou University of Chinese Medicine, Guangzhou, China, ²Guangzhou University of Chinese Medicine; The second Affiliated hospital of Guangzhou University of Chinese Medicine;, Guangzhou, China, ³Clinical Science,Philips Healthcare;, Shanghai, China

We explore the utility of 3D APTw imaging and DKI in assessing the pathological factors of rectal adenocarcinoma. The mean APTSI and MK was higher with the advanced staging and grading in rectal adenocarcinoma. In addition, the mean APTw SI have a significantly positive correlation with WHO grades. Therefore, the mean APTw SI is promising to be a non-invasive biomarker in clinical practice and to become a potential predictor for estimating the prognosis of rectal adenocarcinoma.

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