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Abstract #2442

Validation of the Diagnostic Accuracy of Multi-parametric MRI with PI-RADS V2.1 for Detecting Clinically Significant Prostate Cancer

Xiangyu Wang1, Fan Lin1, and Yi Lei1
1The First Affiliated Hospital of Shenzhen University, Shenzhen, China

229 PZ and 270 TZ lesions were included in this study. The proportion of overall PCa and clinically important PCa detection (Gleason scoreā‰„3+4) for each PI-RADS version 2.1 category was determined. The performance of PI-RADS version 2.1 in cancer detection was evaluated. The diagnostic accuracy of the overall(82.6%) and csPCa TZ lesions(83.0%) is higher than the accuracy of PZ lesions(80.4%, 77.7%). For the csPCa diagnosis, the AUCs of PI-RADS version 2.1 in TZ(0.84) was higher than in PZ(0.77) without significance(P=0.06). Higher PI-RADS version 2.1 scores were associated with increasing likelihood of the presence of clinically important PCa (P<0.01).

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