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Abstract #2464

Is renal blood supply a predictor of protein synthesis in the kidney? A preliminary study in the healthy population

Lihua Chen1, Ailian Liu1, Jiangzheng Wang2, Zhiwei Shen2, Qingwei Song1, Renwang Pu1, and Nan Wang1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China

3D amide proton transfer weighted (APTw) MR imaging is a novelcontrast-agent-free MRI technique for detection of amide protons in mobile cellular proteins and peptides 1-3.On the other hand, 3D pseudo-continuous arterial spin labeling (3D-pCASL)is amethod to measure renal blood supply and hence potentially a metric for renal function. This study reveals a close association between the vascularity and concentration of mobile cellular proteins in kidney.

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