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Abstract #2466

In-vivo 19F-isoflurane MR imaging in adipose tissue

Gang Zheng1, Michael de Veer1, Hongxin Wang1, Shenpeng Li1, and Gary Egan1
1Monash Biomedical Imaging, Monash University, Clayton, Australia

The detection of adipose tissue (AT) is of great importance in studying obesity. Isoflurane is a common fluorinated anesthetic with an excellent safety record in preclinical studies, which has a high blood–gas partition coefficient in adipose tissue. This abstract demonstrates that 19F-isoflurane can be used as an MR contrast agent for noninvasive imaging of AT in a mouse body.

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