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Abstract #2472

Comparison of Mono-, Bi-, and Stretched Exponential Diffusion-weighted MR Imaging in Differentiating Hepatic Hemangiomas and Liver Metastases

Yoshifumi Noda1, Keita Fujimoto1, Nobuyuki Kawai1, Kimihiro Kajta1, Yuta Akamine2, Hiroshi Kawada1, Yukichi Tanahashi1, and Masayuki Matsuo1
1Radiology, Gifu University, Gifu, Japan, 2Philips Japan, Tokyo, Japan

Intravoxel incoherent motion, a bi-exponential model of diffusion-weighted imaging with multiple b values, can represent pure molecular diffusion and perfusion, and be used in characterizing focal hepatic lesions. Recently, stretched exponential model has been used in several cancers. In this study, we evaluated the feasibility of stretched exponential model for differentiating hepatic hemangiomas and liver metastases. Our results showed that DDC value from a stretched exponential model was the highest diagnostic potential, so it could be a quantitative imaging biomarker for differentiating hepatic hemangiomas and liver metastases.

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