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Abstract #2483

Gd-BOPTA-enhanced MRI predicts the severity of esophageal varices (EV) and portal vein pressure in hepatitis B cirrhosis patients

Xinya Zhao1, Xianshun Yuan1, Mengxiao Liu2, Xiang Feng3, Xiangtao Lin1, and Ximing Wang1
1Department of Radiology, Shandong Provincial Hospital, Jinan, China, 2MR Scientific Marketing, Diagnostic Imaging, Siemens Healthcare Ltd, shanghai, China, 3MR Scientific Marketing, Diagnostic Imaging, Siemens Healthcare Ltd, Beijing, China

The characteristics of liver cirrhosis are usually hepatic dysfunction and portal hypertension. Portal hypertension further leads to ascites and esophageal varices (EV). To our knowledge, no methods are currently available for the simultaneous evaluation of portal hypertension and EV severity. The results of this study positively illustrate that Gd-BOPTA-enhanced MRI can serve as a novel and efficient tool to simultaneously and accurately evaluate portal hypertension and high-risk EVs. Relative enhancement ratio (RE) is correlated with estimated HVPG. The formula (-6.483+15.612*portal vein width + 2.251 * RE - 0.176 * platelet count) could be used for the prediction of high-risk EVs.

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