In recent years, population of non-alcoholic fatty liver diseases (NAFLD) have shown a trend of increasing. Besides, studies have reported that NAFLD was associated with pancreatic fat infiltration. 3D mDixon Quant has been widely used for evaluation of fat fraction in various organs/tissues. In the present study, the 3D mDixon Quant sequence was employed to assess the relationship between liver and pancreatic fat contents. Results suggested that there was a significant positive correlation between liver and pancreatic fat contents (r=0.624, P<0.05), which may be helpful for clinical diagnoses.