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Abstract #2521

Clinical value of N-acetyl mucinous compounds and lipid peaks in differentiating benign and malignant ovarian mucinous tumors by MR spectroscopy

Mayumi Takeuchi1, Kenji Matsuzaki2, and Masafumi Harada1
1Department of Radiology, Tokushima University, Tokushima, Japan, 2Department of Radiological Technology, Tokushima Bunri University, Sanuki-city, Japan

MR spectroscopy of pathologically proven 26 ovarian mucinous tumors (9 benign and 17 malignant) was retrospectively evaluated. N-acetyl mucinous compounds (NAMC) peak at 2 ppm was observed in all 26 lesions. Lipid peak was observed in 1 of 9 benign tumors (11%) and 12 of 17 malignant tumors (71%). The presence of lipid peak for the diagnosis of malignancy had a sensitivity of 71%, specificity of 89%, PPV of 92%, and NPV of 62%. We conclude that the bimodal peaks of NAMC and necrosis-associated lipid are suggestive of malignant mucinous tumors.

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