It is challenging to perform diffusion-weighted imaging (DWI) on thyroid gland with high quality due to susceptibility artifacts caused by complex structure compositions, and physiological motion artifacts and low signal-to-noise ratio (SNR) using conventional head and neck joint coil. We used a histogram-based approach to evaluate the images of the small field-of-view (FOV) DWI (Focus, GE) and DWI with short-tau inversion-recovery (STIR) fat suppression using a state-of-the-art surface-coil specifically designed for thyroid gland. We found significantly different level and considerably inhomogeneity in signal intensity between right and left lobe of thyroid gland and between two DWIs.
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