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Abstract #2629

Quantitative Assessment of Liver Function by using Gd-EOB-DTPA-Enhanced MRI: Hepatocyte Fraction

Xueqin ZHANG1, Jian LU1, Jifeng JIANG1, and Weibo CHEN2
1the Third People’s Hospital of Nantong, Nantong, China, 2Philips Healthcare, Shanghai, China

The purpose of this study was to assess the ability of hepatocyte fraction on Gd-EOB-DTPA-enhanced MRI for the quantitative evaluation of liver function. 69 patients with cirrhosis and 22 healthy volunteers with normal liver function who underwent Gd-EOB-DTPA enhanced MRI were collected in this study. T1 mapping images were obtained by using the Look-Locker sequences before and 20 minutes after Gd-EOB-DTPA administration, hepatocyte fraction (HeF) and KHep were measured. Our study showed that hepatocyte fraction (HeF and KHep vlaues) based on Gd-EOB-DTPA- enhanced T1 mapping MRI is an efficient diagnostic tool for the quantitative evaluation of liver function.

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