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Abstract #2631

The value of texture analysis based on multiple high b-values DWI for evaluation of tumor heterogeneity in HCC patients

Ying Zhao1, Jiazheng Wang2, Zhiwei Shen2, Zhongping Zhang2, Nan Wang1, Lihua Chen1, Dahua Cui1, Tao Lin1, Qingwei Song1, Renwang Pu1, Bingbing Gao1, and Ailian Liu1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China

Previous studies have reported preliminary but promising results that high b‐value DWI has a remarkably high sensitivity in neuro or genitourinary malignancies. However, the value of high b-value DWI in liver remains controversial. In the current study, multiple high b-values DWI - based texture analysis was applied to evaluate tumor heterogeneity in hepatocellular carcinoma (HCC) patients. The results demonstrated that ultra-high b-value (b = 2000 and 3000 s/mm2) DWI images could offer more information in tumor heterogeneity evaluation compared to the conventional b-value (b = 800 s/mm2) DWI images based on texture analysis in HCC patients.

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