Abstract #2631

The value of texture analysis based on multiple high b-values DWI for evaluation of tumor heterogeneity in HCC patients

Ying Zhao¹, Jiazheng Wang², Zhiwei Shen², Zhongping Zhang², Nan Wang¹, Lihua Chen¹, Dahua Cui¹, Tao Lin¹, Qingwei Song¹, Renwang Pu¹, Bingbing Gao¹, and Ailian Liu¹

¹The First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Philips Healthcare, Beijing, China

Previous studies have reported preliminary but promising results that high b‐value DWI has a remarkably high sensitivity in neuro or genitourinary malignancies. However, the value of high b-value DWI in liver remains controversial. In the current study, multiple high b-values DWI - based texture analysis was applied to evaluate tumor heterogeneity in hepatocellular carcinoma (HCC) patients. The results demonstrated that ultra-high b-value (b = 2000 and 3000 s/mm²) DWI images could offer more information in tumor heterogeneity evaluation compared to the conventional b-value (b = 800 s/mm²) DWI images based on texture analysis in HCC patients.

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