Abstract #2644

Application of the Free-Breathing 3D Turbo Gradient Spin Echo pCASL Sequence to Assess Renal Perfusion in Patients with Diabetic Nephropathy

Xiao-dong Zheng¹, Shi-hong Li¹, Guang-wu Lin¹, Cai-xia Fu², and Bernd Kühn³

¹Department of Radiology, Hua Dong Hospital, Fudan University, Shanghai, China, ²MR Application Development, Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, ³MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany

In this study, we aimed to compare the renal blood flow (RBF) values obtained with the 3D Turbo Gradient Spin Echo (TGSE) pCASL sequence with glomerular filtration rates (GFRs) measured using single-photon emission computed tomography (SPECT) for nuclide nephro-dynamic imaging to assess renal perfusion in patients with diabetic nephropathy. Our study demonstrated that the RBF values were well correlated with GFR, indicating that the 3D-TGSE pCASL sequence could be used as an alternative - method for the prediction of early diabetic nephropathy.

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