MRI imaging is a radiographic imaging technology widely used in human body. The application of MRI at the molecular level had became a hot research topic in the near future. 3D amide proton transfer weighted(APTw) MR imaging is a new contrast-agent-free MRI technique that addresses the need for a more confident diagnosis in oncology[1,2]. The APTw was widely used in the nervous system. Recently, The APTw was gradually applied to the abdomen[3,4]. At present, there is no related research reported on renal APT imaging.