Radiomic features were automatically extracted from tibial bone using knee MRI data of 665 women and the ability of the features to discriminate subjects with and without osteoarthritis was assessed. An area under the receiver operating characteristics curve of 0.80 was obtained for classifying subjects with and without osteoarthritis using an elastic net regression model that included radiomic features and covariates. Our results indicate that tibial bone characteristics are different between subjects with and without knee osteoarthritis.
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