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Abstract #2715

A method for quantification of changes in leg muscle fiber orientations

Laura Secondulfo1, Joep J M Suskens2, Ozgur Kilic2, Valentina Mazzoli3, Mario Maas4, Hans J.L Tol2, Aart Nederveen4, Melissa Hooijmans1, and Gustav J Strijkers1
1Biomedical Engineering and Physics, UMC Amsterdam, Location AMC, Amsterdam, Netherlands, 2Orthopedic Surgery, UMC Amsterdam, Location AMC, Amsterdam, Netherlands, 3Radiology, Lucas Center for Imaging, Stanford University, Stanford, CA, United States, 4Radiology and Nuclear Medicine, UMC, Amsterdam, Location AMC, Amsterdam, Netherlands

Hamstring injuries have high recurrence rates in elite athletes, which motivates the investigations in novel diagnostic methods for muscle injury and follow-up. Diffusion tensor imaging facilitates direct and indirect monitoring of the muscle condition and architecture. Fiber orientations and changes therein due to injury or training are considered a key parameter; however, the assessment over the full volume of an individual muscle is still difficult. Therefore, we developed a method to generate reproducible quantitative fiber-angle color maps of the whole volume of leg muscles, which proved sensitive to changes due to muscle stretch and a training intervention.

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