Meeting Banner
Abstract #2730

Scan-Rescan Variability and Left-Right Knee Asymmetry of Cartilage Morphometry Assessed with Rapid MRI in a Harmonized Multi-Vendor Study

Akshay Chaudhari1, Quin Lu2, Anna Wisser3,4, Wolfgang Wirth3,4, Garry E Gold1, Brian A Hargreaves1, and Felix Eckstein3,4
1Stanford University, Stanford, CA, United States, 2Philips, San Francisco, CA, United States, 3Paracelsus Medical University, Salzburg, Austria, 4Chondrometrics GmbH, Ainring, Germany

Changes in cartilage morphology have shown to predict and monitor osteoarthritis progression with great sensitivity. However, the lack of a rapid and inexpensive MRI technique for imaging cartilage that can be implemented across vendors is a challenge in large multi-site clinical studies. In this work, we evaluate multi-vendor and scan-rescan reliability and explore left-right knee asymmetries of cartilage morphology measured using a rapid, 4-minute quantitative double-echo steady-state (qDESS) sequence. We demonstrate qDESS harmonization across vendors, which can produce high scan-rescan repeatability and high repeatability of left-right knee asymmetry of cartilage volume, surface area, and thickness metrics.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords