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Abstract #2761

Vertebral Marrow Microenvironment Indexes in Middle-aged and Elderly People with Varying Bone Mineral Density: Functional MRI Evaluation

Jingqi Zhu1, Xueli Zhang1, Yun Tu1, Rui Tang1, Rui Ji1, Jilei Zhang2, Ting Hua1, and Guangyu Tang*1
1Department of Radiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China, 2Clinical Science, Philips Healthcare, Shanghai, China

Our study found that the differences of the parameters of mDIXON-Quant and IVIM-DWI [T2*, fat fraction (FF) and f values] among three groups with varying bone mineral density (normal, osteopenic and osteoporotic) were statistically significant. The correlations of the T2* and FF values with T-score were negative and the correlations of the D* and f values with T-score were positive. Our study implies that mDIXON-Quant and IVIM-DWI techniques were helpful to reflect the changes of vertebral marrow microenvironment of osteoporosis, which may provide valuable information for the assessment of the bone quality.

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