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Abstract #2763

Gender-related variation of IVIM diffusion weighted imaging observed in lumbar vertebral bone marrow: a healthy volunteer study

Fan Qing1, Ren Huipeng1, Wang Xiaohu1, Shen Tianbo1, Wei Xiaocheng2, and Ren Zhuanqin1
1Baoji Central Hospital, Shaanxi Province, Baoji, China, 2GE Healthcare, MR Research China, Beijing, China

Despite the fact that diffusion MRI is well established in bone marrow as a valuable imaging modality, only a limited number of studies have investigated the intravoxel incoherent motion (IVIM) approach. In this study, bi-exponential IVIM was used to measure diffusion and perfusion fraction in lumbar vertebral bone marrow in 99 healthy subjects. The results demonstrated a gender-related variation in D and f while D* was an independent factor. Our findings may help to better understand the variation of water diffusion and perfusion imaging in lumbar vertebral bone marrow in-vivo with healthy and pathological condition.

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