Osteoporosis is characterized by a loss in bone mass and structural decrease of bone tissue which is leading to morbidity and an increased fracture risk. Fractures occur predominantly in areas with trabecular bone and the assessment of the bone volume and microstructural changes in the trabecular bone are therefore highly relevant in fracture prediction. The present study characterizes the decay of trabecularized bone marrow signal in multi-echo imaging sampling both UTEs and conventional TEs. A novel methodology is proposed for simultaneous cortical and trabecular bone imaging in the presence of bone marrow.
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