Abstract #2770

Simultaneous evaluation of bone and cartilage status in asymptomatic FAI subjects and healthy controls using PET-MRI

Gerd Melkus^1,2, Kawan Rakhra^1,2, Reggie Taylor³, Katie Dinelle³, Stephen Dinning^4,5, and Paul Beaulé^5,6

¹Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada, ²Radiology, University of Ottawa, Ottawa, ON, Canada, ³Brain Imaging Centre, The Royal Hospital, Ottawa, ON, Canada, ⁴Nuclear Medicine, The Ottawa Hospital, Ottawa, ON, Canada, ⁵Medicine, University of Ottawa, Ottawa, ON, Canada, ⁶Orthopaedic Surgery, The Ottawa Hospital, Ottawa, ON, Canada

In this study subjects with asymptomatic FAI and healthy controls underwent PET-MRI to investigate hip bone activity (by [18F]-Sodium Fluoride (NaF) PET) and hip cartilage proteoglycan content (by MRI T1ρ mapping). The FAI subjects showed an increased [18F]-NaF uptake in the femoral head neck junction and in lateral area of the acetabulum, indicating increased bone remodelling. Hip cartilage T1ρ values were significantly higher in the anterior-lateral region for the FAI group, revealing a loss of proteoglycan with a possible connection to an early osteoarthritis stage. PET-MRI has potential to be a useful non-invasive tool to research FAI in vivo.

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