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Abstract #2770

Simultaneous evaluation of bone and cartilage status in asymptomatic FAI subjects and healthy controls using PET-MRI

Gerd Melkus1,2, Kawan Rakhra1,2, Reggie Taylor3, Katie Dinelle3, Stephen Dinning4,5, and Paul Beaulé5,6
1Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada, 2Radiology, University of Ottawa, Ottawa, ON, Canada, 3Brain Imaging Centre, The Royal Hospital, Ottawa, ON, Canada, 4Nuclear Medicine, The Ottawa Hospital, Ottawa, ON, Canada, 5Medicine, University of Ottawa, Ottawa, ON, Canada, 6Orthopaedic Surgery, The Ottawa Hospital, Ottawa, ON, Canada

In this study subjects with asymptomatic FAI and healthy controls underwent PET-MRI to investigate hip bone activity (by [18F]-Sodium Fluoride (NaF) PET) and hip cartilage proteoglycan content (by MRI T1ρ mapping). The FAI subjects showed an increased [18F]-NaF uptake in the femoral head neck junction and in lateral area of the acetabulum, indicating increased bone remodelling. Hip cartilage T1ρ values were significantly higher in the anterior-lateral region for the FAI group, revealing a loss of proteoglycan with a possible connection to an early osteoarthritis stage. PET-MRI has potential to be a useful non-invasive tool to research FAI in vivo.

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