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Abstract #2778

MRI models of the Age-Related Bone Loss: Insights from Multi-modal Imaging Study

Malakeh Malekzadeh1, Shahrokh Abbasi-Rad 2, Mohammad Bagher Shiran1, Mojgan Asadi3, Mehdi Shamsi4, Navid Tofighi Rad4, and Hamidreza Saligheh Rad5
1Iran University of Medical Science, Tehran, Iran (Islamic Republic of), 2Quantitative Medical Imaging Systems Group, Tehran, Iran (Islamic Republic of), 3Tehran University of Medical Science, Tehran, Iran (Islamic Republic of), 4Laleh Hospital, Tehran, Iran (Islamic Republic of), 5Tehran University of medical science, Tehran, Iran (Islamic Republic of)

This study deals with assessing the ability of current clinical measures of bone to model the systematic age-related alteration of bone during aging and where does MRI stand as a new modality. Fifty Healthy volunteers with an average age of 44.53 ±7.95 were enrolled based on oral interviews and blood tests. Quantitative measurements were performed by various modalities for lumbar spine, forearm (DXA), Calcaneus (QUS), and Tiba (QCT and MRI). Pearson correlation coefficients was calculated between the bone parameters and age. The highest correlation coefficient between bone parameters and age was related to T1 (r = 0.766, p <0.01).

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