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Abstract #2805

The Angular Dependence of 3D Ultrashort Echo Time Cones Adiabatic T1ρ (3D UTE Cones-AdiabT1ρ) Imaging of the Achilles Tendon

Mei Wu1,2, Mingxin Chen1, Yajun Ma1, Akhil Kasibhatla1, Lidi Wan1, Saeed Jerban1, Hyungseok Jang1, Eric Y Chang1,3, and Jiang Du1
1Department of Radiology, University of California, San Diego, San Diego, CA, United States, 2Department of Radiology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou, China, 3Radiology Service, VA San Diego Healthcare System, San Diego, CA, United States

This study investigated the magic angle effect in three-dimensional ultrashort echo time Cones Adiabatic T1ρ (3D UTE Cones-AdiabT1ρ) imaging of the Achilles tendon on a clinical 3T scanner. The magic angle effect was investigated by repeated UTE Cones-AdiabT1ρ imaging of five human Achilles tendon samples at five angular orientations ranging from 0° to 90° relative to the B0 field. Conventional Cones continuous wave T1ρ (Cones­-CW-T1ρ) and Cones-T2* sequences were also applied for comparison. Cones-AdiabT1ρ showed a much reduced magic angle effect as compared to regular Cones-CW-T1ρ and Cones-T2*, suggesting its potential use as a novel biomarker for musculoskeletal (MSK) imaging.

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