Abstract #2805

The Angular Dependence of 3D Ultrashort Echo Time Cones Adiabatic T1ρ (3D UTE Cones-AdiabT1ρ) Imaging of the Achilles Tendon

Mei Wu^1,2, Mingxin Chen¹, Yajun Ma¹, Akhil Kasibhatla¹, Lidi Wan¹, Saeed Jerban¹, Hyungseok Jang¹, Eric Y Chang^1,3, and Jiang Du¹

¹Department of Radiology, University of California, San Diego, San Diego, CA, United States, ²Department of Radiology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou, China, ³Radiology Service, VA San Diego Healthcare System, San Diego, CA, United States

This study investigated the magic angle effect in three-dimensional ultrashort echo time Cones Adiabatic T1ρ (3D UTE Cones-AdiabT1ρ) imaging of the Achilles tendon on a clinical 3T scanner. The magic angle effect was investigated by repeated UTE Cones-AdiabT1ρ imaging of five human Achilles tendon samples at five angular orientations ranging from 0° to 90° relative to the B0 field. Conventional Cones continuous wave T1ρ (Cones-CW-T1ρ) and Cones-T2* sequences were also applied for comparison. Cones-AdiabT1ρ showed a much reduced magic angle effect as compared to regular Cones-CW-T1ρ and Cones-T2*, suggesting its potential use as a novel biomarker for musculoskeletal (MSK) imaging.

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