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Abstract #2819

Effect of room temperature storage on relaxation properties of ex vivo articular cartilage

Olli Nykänen1, Nina Hänninen1,2, and Mikko J Nissi1,2
1Department of Applied Physics, University of Eastern Finland, Kuopio, Finland, 2Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland

Typical measurement protocols for quantitative MRI of ex vivo osteochondral samples may last hours when multiple parameters with high resolution are measured. However, knowledge about the changes in the relaxation properties of articular cartilage during long scans is inadequate. In this study, we measured T1, adiabatic T1rho and T2-relaxation times for two osteochondral samples directly after sample preparation and repeated the measurements after 15 hours of storage at room temperature. T1-relaxation time decreased noticeably at later timepoint while adiabatic T1rho and T2-relaxation times remained the same. Due to small sample size, statistical significance of the results could not be verified.

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