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Abstract #2928

Respiratory-triggered quantitative MR spectroscopy of the human spinal cord at 7 T

Tangi Roussel1,2, Yann Le Fur1,2, Jean-Philippe Ranjeva1,2, and Virginie Callot1,2
1Aix-Marseille Univ, CNRS, CRMBM, Marseille, France, 2APHM, Hôpital Universitaire Timone, CEMEREM, Marseille, France

1H MR spectroscopy (MRS) is of great interest to help characterizing human spinal cord pathologies. However, few studies have been reported so far because of challenging experimental difficulties caused by the small size of the structure, static and radiofrequency field heterogeneities, as well as physiological motion and especially breathing. In this work, we demonstrate the necessity of respiratory-gated acquisition to collect robust 1H MRS data from the cervical spinal cord at 7T. We also present dedicated post-processing and quantitative approaches for SC metabolic assessment.

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