Abstract #3117

Accelerated 3D chemical exchange saturation transfer imaging using compressed SENSE for full Z-spectrum acquisition

Tatsuhiro Wada¹, Chiaki Tokunaga¹, Osamu Togao², Masami Yoneyama³, Yasuo Yamashita¹, Kouji Kobayashi¹, Toyoyuki Kato¹, and Hidetake Yabuuchi⁴

¹Division of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan, ²Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, ³Philips Japan, Fukuoka, Japan, ⁴Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan

Multi-slice chemical exchange saturation transfer (CEST) imaging is difficult to use for clinical studies because data acquisition of the full z-spectrum is time-consuming. To accelerate the scan time for obtaining multi-slice CEST imaging, we applied the compressed sensing (CS) and sensitivity encoding (SENSE) technique (CS-SENSE) to 3D CEST imaging. The 3D CEST imaging combined with CS-SENSE was obtained without reducing the image contrast of the 2D CEST imaging. Moreover, 10 slice CEST images could be acquired in approximately 7 minutes including B0 map. 3D CEST imaging combined with CS-SENSE was shown to be useful for clinical study.

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