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Abstract #3117

Accelerated 3D chemical exchange saturation transfer imaging using compressed SENSE for full Z-spectrum acquisition

Tatsuhiro Wada1, Chiaki Tokunaga1, Osamu Togao2, Masami Yoneyama3, Yasuo Yamashita1, Kouji Kobayashi1, Toyoyuki Kato1, and Hidetake Yabuuchi4
1Division of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan, 2Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 3Philips Japan, Fukuoka, Japan, 4Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan

Multi-slice chemical exchange saturation transfer (CEST) imaging is difficult to use for clinical studies because data acquisition of the full z-spectrum is time-consuming. To accelerate the scan time for obtaining multi-slice CEST imaging, we applied the compressed sensing (CS) and sensitivity encoding (SENSE) technique (CS-SENSE) to 3D CEST imaging. The 3D CEST imaging combined with CS-SENSE was obtained without reducing the image contrast of the 2D CEST imaging. Moreover, 10 slice CEST images could be acquired in approximately 7 minutes including B0 map. 3D CEST imaging combined with CS-SENSE was shown to be useful for clinical study.

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