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Abstract #3187

Experimental Validation of Conductivity Tensor Imaging using Giant Vesicle Suspension

In Ok Ko1, Bup Kyung Choi2, Nitish Katoch2, Ji Ae Park1, Yong Soo Cho3, Jin Woong Kim3, Hyung Joong Kim2, and Eung Je Woo2
1Korea Institute of Radiological and Medical Sciences, Seoul, Korea, Republic of, 2Kyung Hee University, Seoul, Korea, Republic of, 3Chosun University Hospital and Chosun University College of Medicine, Gwangju, Korea, Republic of

Conductivity tensor can realize volume conductor model of brain for neuroimaging and electrical stimulation. We report validation of electrodeless conductivity tensor imaging (CTI) method [1]. From CTI imaging using giant vesicle suspension at 9.4T MRI, relative error in conductivity tensor image was found to be less than 1.7% compared with the measured values using an impedance analyzer. High- and low-frequency conductivity can quantify total and extracellular water contents, respectively, at every pixel. Their difference can quantify intracellular water content at every pixel. Current CTI method can separately quantify the contributions of ion concentrations and mobility to the conductivity tensor.

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