Abstract #3216

The effect of voxel size on magnetic susceptibility and R2* of intramyocardial hemorrhage at 3 and 7 T

Brianna F. Moon¹, Srikant Kamesh Iyer², Nicholas J. Josselyn², James J. Pilla², Joseph H. Gorman III³, Robert C. Gorman³, Cory Tschabrunn⁴, Giovanni Ferrari⁵, Yuchi Han⁴, Harold I. Litt², and Walter R. Witschey²

¹Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, ²Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, ³Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, ⁴Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, ⁵Surgery, Columbia University Irving Medical Center, New York City, NY, United States

Intramyocardial hemorrhage is a complication of reperfused myocardial infarction. Quantitative susceptibility mapping (QSM), R2*-mapping and T2*-weighted images provide quantitative assessment and image contrast based on the presence of iron. We sought to determine the relationship between magnetic susceptibility and R2* with varying voxel size at 3 and 7 T, where tissue magnetic susceptibility showed independence of field strength but dependence on voxel size. At high resolution the detection of heterogeneous infarct magnetic susceptibility improved in a large animal model of myocardial infarction.

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