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Abstract #3216

The effect of voxel size on magnetic susceptibility and R2* of intramyocardial hemorrhage at 3 and 7 T

Brianna F. Moon1, Srikant Kamesh Iyer2, Nicholas J. Josselyn2, James J. Pilla2, Joseph H. Gorman III3, Robert C. Gorman3, Cory Tschabrunn4, Giovanni Ferrari5, Yuchi Han4, Harold I. Litt2, and Walter R. Witschey2
1Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, 2Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, 3Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, 4Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, 5Surgery, Columbia University Irving Medical Center, New York City, NY, United States

Intramyocardial hemorrhage is a complication of reperfused myocardial infarction. Quantitative susceptibility mapping (QSM), R2*-mapping and T2*-weighted images provide quantitative assessment and image contrast based on the presence of iron. We sought to determine the relationship between magnetic susceptibility and R2* with varying voxel size at 3 and 7 T, where tissue magnetic susceptibility showed independence of field strength but dependence on voxel size. At high resolution the detection of heterogeneous infarct magnetic susceptibility improved in a large animal model of myocardial infarction.

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