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Abstract #3280

Comparison of k-space filtering and variable flip angle schemes for reduced T2 blurring in 3D ASL MRI

Yiming Wang1, Limin Zhou1, Sheng Qing Lin1, Joshua S. Greer1,2, and Ananth J. Madhuranthakam1,3
1Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 2Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

3D arterial spin labeled (ASL) MRI using turbo spin echo (TSE) based acquisitions suffer from image blurring, due to T2 decay along the echo train. To date, several methods have been proposed to reduce T2 blurring, including k-space filtering and variable flip angle schemes. In this study, the performances of k-space filtering was compared with variable flip angle scheme to compensate or reduce T2 blurring of 3D ASL images acquired with Cartesian TSE. Results showed k-space filtered images provided similar sharpness improvement compared with variable flip angle method.

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