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Abstract #3296

Low-Rank Reconstruction for Multi-Delay Arterial Spin Labeling

Paul Kyu Han1, Yanis Djebra1,2, Thibault Marin1, Georges El Fakhri1, Jinsong Ouyang1, and Chao Ma1
1Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States, 2LTCI, Télécom Paris, Institut Polytechnique de Paris, Palaiseau, France

Multi-delay arterial spin labeling (ASL) is a powerful MRI technique that allows to non-invasively measure both cerebral blood flow and arterial transit time quantitatively, which has great potential for clinical applications. However, usage of multi-delay ASL is limited by the prolonged scan time with the number of post-labeling delay times used for acquisition. Up to date, low-rank property has been observed in signals of various MR applications where low-rank approach has demonstrated promising results. This work shows that the dynamics of ASL signal display low-rank property and the scan time of multi-delay ASL can be accelerated using low-rank image reconstruction.

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