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Abstract #3309

Simultaneous Fat-Water MR Elastography Imaging using Distortion-free DIADEM-EPI

Yi Sui1, MyungHo In1, Armando Manduca2, Matthew A. Bernstein1, Richard L. Ehman1, John III Huston1, and Ziying Yin1
1Radiology, Mayo Clinic, Rochester, MN, United States, 2Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States

Simultaneous fat-water EPI-MR elastography imaging was developed for acquisition of the brain (water) and skull (bone marrow fat) MRE motion. Compared to our previous dual-saturation and dual-sensitivity motion encoding (DSDM) technique, the proposed method minimize the EPI distortion and misalignment between skull and brain. This technique could offer a unique opportunity to quantify the skull-brain mechanical decoupling performance modulated by the pia-arachnoid complex, and its potential alterations in response to repetitive head impacts (RHI) in our future studies.

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