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Abstract #3338

Quantitative abdominal imaging using 3D motion-robust MR fingerprinting

Max van Riel1,2, Zidan Yu2,3, Shota Hodono2,3, Ding Xia2, Hersh Chandarana2, and Martijn A. Cloos2,3
1Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, 2Center for Advanced Imaging Innovation and Research and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 3Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY, United States

We demonstrate a 3D MR fingerprinting sequence for quantitative abdominal imaging. The sequence was made robust to motion by modifying the order of acquisition to allow for free-breathing imaging. Furthermore, the flip angle pattern was optimized using the Cramér-Rao Lower Bound to increase the efficiency of the sequence. A phantom was used to validate the new sequence and it was shown that the motion-robust ordering reduced motion-related artefacts. In vivo results showed reduced artefacts as well. We conclude that it is possible to generate B1-robust quantitative T1 and proton density maps at a clinically usable resolution within 5 minutes.

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