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Abstract #3356

Prospectively corrected dual-echo EPI using optical tracking

Onur Afacan1, W. Scott Hoge2, Tess E. Wallace1, Tobias Kober3,4,5, Daniel Nicolas Splitthoff6, Ali Gholipour1, Sila Kurugol1, Camilo J. Cobos1, Richard L. Robertson1, and Simon K. Warfield1
1Department of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States, 2Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States, 3Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 4Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 5École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 6Siemens Healthcare, Erlangen, Germany

Large head motion induces different local magnetic-field inhomogeneities, even if the field of view is corrected prospectively. In this work, we implemented and evaluated a diffusion-weighted dual-echo EPI sequence that prospectively corrects for motion using real-time measurements from an optical tracker and uses echoes acquired with reversed phase-encoding to correct for the distortions resulting from the induced local magnetic field inhomogeneities. We evaluated our motion and distortion correction framework in volunteer experiments undergoing controlled motion, and in pediatric patients undergoing routine MRI. Prospective motion correction using our proposed method produced high-quality diffusion parameter maps in all volunteer and patient scans.

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