Abstract #3359

Motion Correction Strategy for Multi-Contrast based 3D parametric imaging: Application to Inhomogeneous Magnetization Transfer (ihMT)

Lucas Soustelle^1,2, Julien Lamy³, Arnaud Le Troter^1,2, Patrick Viout^1,2, Lauriane Pini^1,2, Claire Costes^1,2, Jean-Philippe Ranjeva^1,2, Maxime Guye^1,2, Adil Maarouf^1,2,4, Bertrand Audoin^1,2,4, Clémence Boutière^1,2,4, Audrey Rico^1,2,4, Gopal Varma⁵, David C Alsop⁵, Jean Pelletier^1,2,4, Olivier M Girard^1,2, and Guillaume Duhamel^1,2

¹Aix-Marseille Univ, CNRS, CRMBM, Marseille, France, ²APHM, Hôpital Universitaire Timone, CEMEREM, Marseille, France, ³Université de Strasbourg, CNRS, ICube, FMTS, Strasbourg, France, ⁴APHM, Hôpital Universitaire Timone, Service de neurologie, Marseille, France, ⁵Division of MR Research, Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States

Multi-contrast-based parametric MRI techniques provide parametric maps intrinsically sensitive to voxel misalignment upon images combination.

In this work, we propose an efficient retrospective motion correction method adapted to this problem, with an application to inhomogeneous Magnetization Transfer (ihMT) imaging. The proposed method is confronted with the MCFLIRT (FSL) method used as reference, and residual motion is quantified and analysed across native and motion corrected images.

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