Abstract #3375

Highly-accelerated Compressed Sensing 4D Flow MRI for Quantification of Whole Heart Hemodynamics

Daniel Gordon¹, Allison Blake¹, Liliana Ma¹, Yoshihiro Tanaka¹, Kelvin Chow^1,2, Ning Jin³, Philip Greenland¹, Rod Passman¹, Daniel Kim¹, and Michael Markl¹

¹Northwestern University, Chicago, IL, United States, ²Siemens Medical Solutions USA, Inc., Chicago, IL, United States, ³Siemens Medical Solutions USA, Inc., Cleveland, OH, United States

The purpose of this study was to evaluate an efficient, free-breathing, whole-heart 4D flow CS protocol in a cohort of 21 healthy controls. The CS technique was evaluated for internal self-consistency by comparing net flow through various cardiac structures. In addition, cine imaging was performed and used to calculate left ventricular (LV) stroke volume (SV) for comparison to net flow in the ascending aorta. CS whole-heart 4D flow was acquired in 5:23 ± 0:51 minutes. Input and output flow, and LV stroke volume and ascending aorta net volume with 4D flow were significantly (p<0.05) correlated for all comparisons.

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