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Abstract #3379

Hyperpolarized 13C imaging with multi-shot multi-echo echo planar imaging

Kofi Deh1, Kristin Granlund1, Roozbeh Eskandari1, Arsen Mamakhanyan1, Nathaniel Kim1, and Kayvan Keshari,1
1Memorial Sloan Kettering Cancer Center, New York, NY, United States

We demonstrate the use of a use of a broadband RF excitation with a multi-shot EPI readout for robust separation of metabolites in hyperpolarized 13C imaging. The approach places less demands on scanner hardware and compensates for local B0 inhomogeneity, making it possible to obtain high resolution time-resolved multi-slice imaging over a large region of interest which can be reformatted into 3D volumetric images to facilitate the study diseases such as cancer metastasis using HP probes.

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