Fluorine MR methods support quantification but have inherently low SNR. To enhance sensitivity, SNR-efficient imaging techniques such as RARE and cryogenically-cooled surface RF coils are used. However, transceive surface RF coils show variation in the excitation field, impairing quantification and T1 contrast. We previously showed improved homogeneity using a novel B1 correction method developed for 1H imaging that uses experimental data acquired with a volume resonator. Here, we compared it to a sensitivity-only correction and a combination of both, to evaluate which approach yields the most accurate contrast and concentration quantification. This work is applicable to different nuclei.
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