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Abstract #3398

Phantom Development for the Standardization of fMRI Data across Multiple Imaging Sites and Scanners

Daisuke Kokuryo1, Chika Sato2, Takashi Itahashi3, Shigeyoshi Saito4, Hiroyuki Ueda1, Etsuko Kumamoto1,5, Toshiya Kaihara1, Nobutada Fujii1, Noriaki Yahata2,6, and Ichio Aoki2,6
1Graduate School of System Informatics, Kobe University, Kobe, Japan, 2National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan, 3Medical Institute of Developmental Disabilities Research, Showa University, Tokyo, Japan, 4Graduate School of Medicine, Osaka University, Suita, Japan, 5Information Science and Technology Center, Kobe University, Kobe, Japan, 6Institute for Quantum Life Science, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan

Establishing data harmonization in fMRI “big data” is necessary to ensure the reliability and reproducibility of fMRI research. Our group recently developed two distinct phantoms: a brain-shaped phantom to correct field heterogeneity and a functional image-specific phantom to calibrate shape distortion and signal irregularity. A preliminary experiment confirmed a shape distortion and signal irregularity caused by field inhomogeneity when using EPI signals, and these were corrected using an affine transformation. Therefore, our developed phantoms have the potential to contribute to achieving fMRI data standardization.

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