Abstract #3398

Phantom Development for the Standardization of fMRI Data across Multiple Imaging Sites and Scanners

Daisuke Kokuryo¹, Chika Sato², Takashi Itahashi³, Shigeyoshi Saito⁴, Hiroyuki Ueda¹, Etsuko Kumamoto^1,5, Toshiya Kaihara¹, Nobutada Fujii¹, Noriaki Yahata^2,6, and Ichio Aoki^2,6

¹Graduate School of System Informatics, Kobe University, Kobe, Japan, ²National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan, ³Medical Institute of Developmental Disabilities Research, Showa University, Tokyo, Japan, ⁴Graduate School of Medicine, Osaka University, Suita, Japan, ⁵Information Science and Technology Center, Kobe University, Kobe, Japan, ⁶Institute for Quantum Life Science, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan

Establishing data harmonization in fMRI “big data” is necessary to ensure the reliability and reproducibility of fMRI research. Our group recently developed two distinct phantoms: a brain-shaped phantom to correct field heterogeneity and a functional image-specific phantom to calibrate shape distortion and signal irregularity. A preliminary experiment confirmed a shape distortion and signal irregularity caused by field inhomogeneity when using EPI signals, and these were corrected using an affine transformation. Therefore, our developed phantoms have the potential to contribute to achieving fMRI data standardization.

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