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Abstract #3499

Free breath T2*-mapping for planning and monitoring the chelation therapy in children with secondary iron overload

Evelina Nazarova1, Galina Tereshchenko1, and Dmitry Kupriyanov2
1Radiology, Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation, 2Philips Healthcare, Imaging Systems, Moscow, Russian Federation

Iron overload represents critical health problem in children with regular transfusional therapy. Breath hold T2* mapping is widely used for the iron quantification, but it is not always feasible in pre-school children without the sedation. We purpose the free breath T2* mapping for the quick monitoring of treatment response to the chelation therapy in pediatric patients.The purposed method demonstrate that free breath T2* mapping is more convenient for the iron quantification in children according to lack of limited by breath hold technique and provides much higher quality images.

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