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Abstract #3507

Joint Reconstruction of Multiparameter MRI Images for Imaging Intratumoral Subpopulations

Shraddha Pandey1,2, Arthur David Snider1, Wilfrido Moreno1, and Natarajan Raghunand2
1Electrical Engineering, University of South Florida, Tampa, FL, United States, 2Cancer Physiology, Moffitt Cancer Research Center, Tampa, FL, United States

Multispectral analysis of multiparametric MRI (mpMRI) images is being explored as an approach to objectively quantify intratumoral heterogeneity. However, acquisition of multiple co-registered parameters maps such as T1, T2, T2* and ADC for this task can be time-consuming. We propose a joint reconstruction method that exploits shared structural information between co-registered MRI parameter maps that provides high similarity between multispectral clusters defined on parameter maps from undersampled data and the ground truth fully-sampled maps of M0, T1, T2 and T2*.

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