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Abstract #3646

Utility of Whole-Liver Histogram and Texture Analysis on T1 Maps in the Risk Stratification of Advanced Fibrosis in NAFLD

Xinxin Xu1, Caixia Fu2, Robert Grimm3, Huimin Lin1, Ruokun Li1, and Fuhua Yan1
1Radiology, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China, 2Siemens healthcare, Shanghai, China, 3Siemens healthcare, Erlangen, Germany

We aim to assess the utility of whole-liver texture analysis on T1 maps for the risk stratification of advanced fibrosis in patients with suspected NAFLD. Our experiments show that whole-liver histogram and texture parameters of T1 maps can distinguish NAFLD patients with an intermediate-to-high risk of advanced fibrosis. A combination of histogram and texture parameters as a multivariate model showed a better diagnostic performance than any sole parameter and noninvasive fibrosis test in risk stratification of advanced fibrosis.

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