Abstract #3646

Utility of Whole-Liver Histogram and Texture Analysis on T1 Maps in the Risk Stratification of Advanced Fibrosis in NAFLD

Xinxin Xu¹, Caixia Fu², Robert Grimm³, Huimin Lin¹, Ruokun Li¹, and Fuhua Yan¹

¹Radiology, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China, ²Siemens healthcare, Shanghai, China, ³Siemens healthcare, Erlangen, Germany

We aim to assess the utility of whole-liver texture analysis on T1 maps for the risk stratification of advanced fibrosis in patients with suspected NAFLD. Our experiments show that whole-liver histogram and texture parameters of T1 maps can distinguish NAFLD patients with an intermediate-to-high risk of advanced fibrosis. A combination of histogram and texture parameters as a multivariate model showed a better diagnostic performance than any sole parameter and noninvasive fibrosis test in risk stratification of advanced fibrosis.

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