Abstract #3668

MRI-based Body Composition Analysis – Reproducibility and Repeatability

Magnus Borga^1,2, André Ahlgren², Thobias Romu², Per Widholm^2,3, Olof Dahlqvist Leinhard^2,3, and Janne West^2,3

¹Department of Biomedical Engineering and Center for Medical Image Science and Visualization (CMIV), Linköping University, Linkoping, Sweden, ²AMRA Medical, Linköping, Sweden, ³Department of Medicine and Health and Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden

This study investigated between-scanner reproducibility and repeatability of a method for MRI-based body composition analysis. Eighteen healthy volunteers were scanned twice on five different MR scanners from three vendors including both 1.5 and 3T, using a 2-point Dixon neck-to-knee imaging protocol. Visceral adipose tissue, abdominal subcutaneous adipose tissue, thigh muscle volume, muscle fat infiltration and liver fat were quantified using AMRA® Researcher. The reproducibility coefficients for the volume measurements ranged from 7 cl (anterior thigh muscles) to 4.2 dl (abdominal subcutaneous adipose tissue). The reproducibility coefficient for muscle fat infiltration was 1.5 percentage points and for liver fat 2.4 pp.

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