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Abstract #3668

MRI-based Body Composition Analysis – Reproducibility and Repeatability

Magnus Borga1,2, André Ahlgren2, Thobias Romu2, Per Widholm2,3, Olof Dahlqvist Leinhard2,3, and Janne West2,3
1Department of Biomedical Engineering and Center for Medical Image Science and Visualization (CMIV), Linköping University, Linkoping, Sweden, 2AMRA Medical, Linköping, Sweden, 3Department of Medicine and Health and Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden

This study investigated between-scanner reproducibility and repeatability of a method for MRI-based body composition analysis. Eighteen healthy volunteers were scanned twice on five different MR scanners from three vendors including both 1.5 and 3T, using a 2-point Dixon neck-to-knee imaging protocol. Visceral adipose tissue, abdominal subcutaneous adipose tissue, thigh muscle volume, muscle fat infiltration and liver fat were quantified using AMRA® Researcher. The reproducibility coefficients for the volume measurements ranged from 7 cl (anterior thigh muscles) to 4.2 dl (abdominal subcutaneous adipose tissue). The reproducibility coefficient for muscle fat infiltration was 1.5 percentage points and for liver fat 2.4 pp.

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