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Abstract #3673

Evaluation of quantitative MRI parameters reproducibility across a major scanner upgrade: the example of T1

Ratthaporn Boonsuth1, Marco Battiston1, Francesco Grussu1,2, Marios C. Yiannakas1, Torben Schneider3, Rebecca S. Samson1, Ferran Prados1, and Claudia A. M. Gandini Wheeler-Kingshott1,4,5
1NMR research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom, 2Centre for Medical Image Computing, Department of Computer Science, University College London, London, United Kingdom, 3Philips Healthcare, Guildford, Surrey, United Kingdom, 4Brain MRI 3T Research Centre, IRCCS Mondino Foundation, Pavia, Italy, 5Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy

Major MRI scanner upgrades are generally required to improve performance and image quality; however, they can also potentially introduce systematic changes in quantitative MRI (qMRI) metrics and affect their accuracy and precision. To date the evaluation of the effect of scanner upgrades has focussed mainly on volumetric measurements, whereas the effect on quantitative parametric maps remains unexplored, especially when comparing analog and digital signal pathways plus multiband. Here we report findings on quantitative T1 to assess the potential effect of scanner upgrades on qMRI. We found negligible differences, suggesting that T1 measurements remain stable following a major scanner upgrade.

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