Abstract #3719

Fast Distortion-Free DWI using PSF-EPI on A 1.5T Clinical MRI Scanner with An 8-Channel Head Coil

Simin Liu¹, Wenpeng Wu², Yishi Wang^1,3, Jieying Zhang¹, Pengcheng Xie², and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Shenzhen Anke High-tech Co., Ltd., Shenzhen, China, ³Philips Healthcare, Beijing, China

DWI is valuable for diagnosing diseases such as stroke and brain tumor. The traditional single-shot EPI is widely used in DWI because of its high acquisition speed, but it suffers from severe geometric distortions. A recently proposed technique, point-spread-function encoded EPI (PSF-EPI) that is highly accelerated by tilted-CAIPI, can achieve fast distortion-free DWI images on 3T scanners with a 32-channel head coil. This study investigated the feasibility of tilted-CAIPI accelerated PSF-EPI on a 1.5T clinical MRI scanner with an 8-channel head coil. Images with high anatomical fidelity and satisfactory SNR were obtained in 1~2.5 min using this technique.

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