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Abstract #3719

Fast Distortion-Free DWI using PSF-EPI on A 1.5T Clinical MRI Scanner with An 8-Channel Head Coil

Simin Liu1, Wenpeng Wu2, Yishi Wang1,3, Jieying Zhang1, Pengcheng Xie2, and Hua Guo1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Shenzhen Anke High-tech Co., Ltd., Shenzhen, China, 3Philips Healthcare, Beijing, China

DWI is valuable for diagnosing diseases such as stroke and brain tumor. The traditional single-shot EPI is widely used in DWI because of its high acquisition speed, but it suffers from severe geometric distortions. A recently proposed technique, point-spread-function encoded EPI (PSF-EPI) that is highly accelerated by tilted-CAIPI, can achieve fast distortion-free DWI images on 3T scanners with a 32-channel head coil. This study investigated the feasibility of tilted-CAIPI accelerated PSF-EPI on a 1.5T clinical MRI scanner with an 8-channel head coil. Images with high anatomical fidelity and satisfactory SNR were obtained in 1~2.5 min using this technique.

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