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Abstract #3736

Retrospective motion correction of three-dimensional Magnetic Resonance Fingerprinting (MRF)

Jan W Kurzawski1,2, Matteo Cencini1,3, Luca Peretti1,3, Pedro A Gomez4, Rolf Schulte5, Graziella Donatelli1,6, Mirco Cosottini1,3, Paolo Cecchi6, Mauro Costagli1,7, Alessandra Retico2, Michela Tosetti1,7, and Guido Buonincontri1,7
1Imago7, Pisa, Italy, 2INFN, Pisa, Italy, 3University of Pisa, Pisa, Italy, 4Technical University of Munich, Munich, Germany, 5GE Healthcare, Munich, Germany, 6Neuroradiology, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy, 7IRCCS Stella Maris, Pisa, Italy

We demonstrate a novel motion correction of 3D magnetic resonance fingerprinting (MRF) using spiral projection k-space trajectory. The motion was corrected using rigid motion parameters extracted from a whole-brain navigator obtained every 7s of imaging. Firstly, we optimized the trajectory ordering in simulation and selected the acquisition scheme that allowed the best navigator for motion correction. Secondly, we applied this scheme to invivo data in healthy subjects scanned first without motion and then while performing a motion paradigm. Our motion correction improved the correlation of motion-corrupted data with motionless data by over 20% for both T1 and T2.

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