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Abstract #3739

Slice Accelerated EPI-based Magnetic Resonance Fingerprinting for Simultaneous Estimation of T1, T2, T2* with Whole-brain Coverage 

Mahdi Khajehim1,2, Thomas Christen3, Fred Tam4, Simon Graham1,4, and J. Jean Chen1,2
1Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Rotman Research Institute, Baycrest Health Sciences, Toronto, ON, Canada, 3Grenoble Institute of Neurosciences, Inserm, Grenoble, France, 4Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Toronto, ON, Canada

Magnetic resonance fingerprinting (MRF) offers a way to quantitatively estimate multiple relaxation parameters with a single scan, but fast MRF estimation of T1, T2, and T2* with a single acquisition remains challenging. Here, a dual-stage EPI-based MRF approach with online image reconstruction is proposed for estimating T1, T2, and T2*. We achieved 1.1x1.1x3 mm3 resolution with minimal distortion, and with the use of simultaneous multi-slice acceleration, our method can provide whole-brain coverage (1.7x1.7x3 mm3) in less than 3 minutes.

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