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Abstract #3748

Reducing off-resonance effects by spatial decorrelation in Magnetic Resonance Fingerprinting

Ronal Manuel Coronado1,2,3, Gastão Lima da Cruz4, Claudia Prieto1,2,4, and Pablo Irarrázaval1,2,3,5
1Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 3Millennium Nucleus for Cardiovascular Magnetic Resonance, Chile, Santiago, Chile, 4School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, London, United Kingdom, 5Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, Santiago, Chile

Magnetic Resonance Fingerprinting (MRF) acquisitions based on balanced Steady State Free Precession (bSSFP) with spiral trajectories produces higher signal noise to ratio (SNR) in comparison to the unbalanced version, nevertheless its usage is hider because of higher sensitivity to off-resonance artifacts. These artifacts affect the quality of parametric values. Here we propose a novel method to decrease these susceptibility distortions by means of spatial decorrelation. We show promising results where off-resonance artifacts were reduced in a realistic brain simulation and standardized T1/T2 phantom acquisition.

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