Abstract #3748

Reducing off-resonance effects by spatial decorrelation in Magnetic Resonance Fingerprinting

Ronal Manuel Coronado^1,2,3, Gastão Lima da Cruz⁴, Claudia Prieto^1,2,4, and Pablo Irarrázaval^1,2,3,5

¹Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, ²Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, ³Millennium Nucleus for Cardiovascular Magnetic Resonance, Chile, Santiago, Chile, ⁴School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, London, United Kingdom, ⁵Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, Santiago, Chile

Magnetic Resonance Fingerprinting (MRF) acquisitions based on balanced Steady State Free Precession (bSSFP) with spiral trajectories produces higher signal noise to ratio (SNR) in comparison to the unbalanced version, nevertheless its usage is hider because of higher sensitivity to off-resonance artifacts. These artifacts affect the quality of parametric values. Here we propose a novel method to decrease these susceptibility distortions by means of spatial decorrelation. We show promising results where off-resonance artifacts were reduced in a realistic brain simulation and standardized T1/T2 phantom acquisition.

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