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Abstract #3766

Natural, multi-contrast and quantitative imaging of the brain using tailored MR fingerprinting

Pavan Poojar1,2, Enlin Qian1, Maggie Fung3, and Sairam Geethanath1,2
1Columbia University Magnetic Resonance Research Center, Columbia University in the City of New York, New York, NY, United States, 2Dayananda Sagar College of Engineering, Bangalore, India, 3GE Healthcare Applied Sciences Laboratory East, New York, New York, NY, United States

Tailored MRF (TMRF) provides scheme to acquire non-synthetic, multi contrast images simultaneously in one sequence by tailoring the acquisition scheme derived in MRF. Natural contrast obtained from TMRF overcomes artifacts observed in MRF such as flow and errors in tissue parameter quantitation. We acquired TMRF and MRF data on the ISMRM/NIST phantom along with gold standard relaxometry data. We also acquired MRF and TMRF data for 5 volunteers and compared the natural and synthetic contrasts; and the relaxometric maps. The TMRF natural contrasts are similar to control experiments and do not contain flow artifacts found in synthetic contrasts.

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