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Abstract #3814

Blindly trusting MRI radiomics? A study on radiomic features repeatability and reproducibility with a dedicated phantom

Linda Bianchini1, João Santinha2, Nuno Loução3, Mário Figueiredo4, Francesca Botta5, Daniela Origgi5, Marta Cremonesi5, Nickolas Papanikolaou2, and Alessandro Lascialfari1
1Università degli Studi di Milano, Milan, Italy, 2Champalimaud Center for the Unknown, Lisbon, Portugal, 3Philips Healthcare, Lisbon, Portugal, 4Instituto de Telecomunicações, Instituto Superior Técnico, Lisbon, Portugal, 5Istituto Europeo di Oncologia (IEO) IRCCS, Milan, Italy

The radiomic features stability when MR scanners of different vendors or magnetic fields are involved is not known and is needed to support clinical studies. A study on the radiomic features repeatability and reproducibility was carried out with a pelvis phantom designed for radiomic purposes on three MR scanners, two of same field but different vendors and two of same vendor but different fields. The crucial results include a consistent percentage loss of features repeatability after phantom repositioning, suggesting the need for a features selection in studies involving patient’s repositioning. The limited reproducibility demands attention when dealing with multicentric studies.

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