Abstract #3838

Characteristics of temporal dynamics of intrinsic brain activity in unmedicated bipolar II disorder with suicidality

JiaYing Gong^1,2, Guanmao Chen¹, Yanbin Jia³, Long Qian⁴, Li Huang¹, and Ying Wang¹

¹Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, China, ²Department of Radiology, Six Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ³Department of Psychiatry, First Affiliated Hospital of Jinan University, Guangzhou, China, ⁴MR Research, GE Healthcare, Beijing, China

The alterations of brain dynamics in bipolar disorder (BD) with suicidality are still unknown. Dynamic amplitude of low-frequency fluctuations (dALFF) was evaluated using sliding window analysis, and the severity of suicidality was predicted using a multivariate regression model between 106 BD II participants. Our findings suggest that alterations of temporal variability in the precuneus/ posterior cingulate cortex (PCC) is a common feature of BD participants, the right temporal lobe involved in impulsivity, social and emotional processing are associated with suicidality in BD II depression

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.