Abstract #3879

Simultaneous multi-slice spiral-out acquisitions for high resolution perfusion fMRI at 7T

Denizhan Kurban¹, Gilad Liberman^1,2, Christian Mirkes³, Sriranga Kashyap¹, Laurentius Huber¹, Debora Niekämper ¹, Dimo Ivanov¹, and Benedikt A Poser ¹

¹Maastricht Brain Imaging Centre (MBIC), Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, ²A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ³Skope MRT, Zürich, Switzerland

At ultra-high fields, high-resolution and large coverage functional perfusion mapping with Arterial Spin Labeling (ASL) becomes challenging due to shorter T2* requiring shorter read-out times and B0 inhomogeneity causing geometric distortions. We address these challenges with a single-shot, highly undersampled, short-TE spiral-out trajectory, and simultaneous multi-slice sampling with incoherent CAIPIRINHA for increased slice coverage. Spiral ASL acquisitions at short TE allows functional perfusion mapping with higher SNR compared to conventional EPI acquisitions, showing potential for high-resolution perfusion fMRI applications at ultra-high field.

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